Views: 22 Author: Site Editor Publish Time: 2021-12-22 Origin: Site
DIRECT POWDER TABLET PRESSING TECHNOLOGY
As a normal and simple production process, the direct powder pressing process of tablet press technology is simple and does not require granulation and drying.
It saves energy consumption and production time, and at the same time, it can also reduce the risks relating to medicine tablet stability caused by production process conditions and save production costs.So it is the preferred tablet pill pressing technology, regardless of whether it is generic drug or innovative drugs, especially suitable for drugs that need to take effect quickly after entering the human body.
However, the powder direct pressing process also has its limitations. Due to its simple process conditions, it has higher requirements for the relative features of the powder. The powder needs to have an appropriate particle size distribution, density, crystal form, fluidity and compressibility, which ensure that the uniformity of effective components, dissolution and other key quality attributes of the final tablet pills can meet the requirements.
But because most of the excipients are difficult to meet the needs, in the powder direct compression process, the types of excipients, usage and dosage, and the processing methods and key process parameters and the control of key process steps is more important. We will talk about it in the next few articles.